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Previcox Emails

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"Amie" (from AU)
From: Fred B.

Sent: Saturday, December 23, 2008 (update)

Hello, Mel

Further to my story about Amie, who died 16th November 2008. I wrote to Merial in Australia and the USA and have heard back from Merial Australia but not Merial USA.

Their head vet in Australia, Dr Claire J.<name withheld> initally telephoned me and said that Previcox was so safe it wasn't possible that our dog could have becomet ill from taking it and no deaths had ever been reported in Australia due to Previcox.

She said that she would carry out an investigation by talking to our vet and the consulting vet who carried out an endoscopy on Amie when she was losing weight, vomiting and had a protein count so low that she was at death's door after taking Previcox for 3 days. Prior to taking the Previcox she was so healthy you wouldn't believe it.

I liken the investigation of Previcox by Merial to an investigation by the police of the police department.

Dr J. got back to me and concluded, after talking with both vets, that Amie had Protein Losing Enteropathy (PLE) and that it had nothing to do with Previcox.

She evaded my question about how it was possible for Amie to suddenly have PLE after 3 days of taking Previcox when she had no signs of ANY illness before starting Previcox. We don't doubt that Amie had PLE, we also are of the opinion that she developed this after 3 days of taking Previcox.

We KNOW that pet owners know their animals so well and are so in tune with them that we feel that the "experts" should sit up and take notice.

We have lived with Amie and her brother Josh for 12 years, 24 hours a day and they have been everywhere and done everything with us. There's not much that we and other loving pet owners don't know about their pets. They are/were our children.

I found Dr J. very biased and unwilling to admit that Previcox was anything but safe.

She also stated that the reports people posted about Previcox on the Internet were anecdotal and without foundation.

She also pooh-poohed Leaky Bowel syndrome as being fanciful and unproven.

She also stated that the vet who had given Amie an endoscopy said there was no sign of intestinal damage, whereas he told my wife in the op theatre that there were bleeding lesions in the stomach/small intestine. We have no doubt that there were caused by 3 days of taking Previcox and caused her PLE.

So, to me, I sense a coverup. My wife is yet to confront the vet with the conflicting details about the lesions, but we will continue to press on and try. We will take it to the Ombudsman and relevant government departments.

Thank you so much for your time and your Web site. You are doing a great service to those who feel so frustrated and sad about the damage done to their pets by the drug companies and the vets who give them lip service.

Sincerely,

Fred B.

From Mel, K911-

Fred,

How would this Dr. Claire J. know of each and every death in AU attributed to Previcox? Is there a blog somewhere for vets only?

I am outraged not only by this smug behaviour but also by the audacity of telling other dog owners just how inaccurate they are about their own dog's health.

The old adage of "money talks" is certainly apparent here and other vet clinics throughout the world. It is interesting to note that only ONE vet has written us stating that he too believes Previcox to be a dangerous drug while others who write are almost chastising in the way they try to suggest that we do not know the facts.

All pretty much have this same line down pat, "We have had no bad instances of using this drug." I follow up with "Please tell me how you go about monitoring the dogs who have been prescribed Previcox and how often you hear of adverse reactions. I would sincerely like to know, please reply."

I have yet to receive
any information from any of these vets who so vehemently deny what others have written regarding the deaths of their dogs.

There are many practicing vets though who do have an animals best interest at heart. The vet who prescribed the Previcox to Rowdy while we were on vacation seemed to be of that sort. He was very upset to learn Rowdy had died.

Vets who know the dangers of this drug, especially for older dogs but choose to protect their financial investment rather than their client are a disgrace to their oath.

 

"Amie" (from AU)
From: Fred B.

Sent: Saturday, November 15, 2008 2:42 PM

 

Hi, last night we lost our friend Amie, Labrador cross, aged 12. She'd had a good life and rewarded us with her love, devotion and trust.
  
In May this year (2008), I was walking Amie and same litter brother, Josh, and being on open land I let them off lead as usual, when in the distance Josh spied a cat climbing a fence post. He took off and Amie followed and there they were jumping and barking at the cat sitting on top of the fence post. I called them off and noticed that Amie was limping. She'd previously had an op for a replacement cruciate ligament in her other rear leg and we were hoping that this wasn't going to be another.
 
The limping didn't ease, so off to the vet and he prescribed a 10 day course of anti-inflammatory Previcox. After a few days on the drug Amie started vomiting and then she had violent diarrhoea. The vet suggested a visit to a canine clinic 3 hours away in Brisbane. She was treated as an emergency case, put on a drip overnight and the next day was given an endoscopy. This was a $3000 exercise, but of course, our dogs are so important that they've always had the best of everything. The endoscopy wasn't conclusive, but some stomach lesions were found. Her protein levels were way down low and the specialist thought it was something similar to Irritable Bowel Syndrome. Other than to prescribe several drugs, he said there wasn't much that he could do.
 
Amie had drugs for controlling the vomiting, controlling the diarrhoea and controlling the pain. she was put on Hills special food, low fat, high protein but her weight loss was dramatic. Always fairly robust, she was shrinking fast and her ribs were very visible and she was losing muscle in her legs. She had trouble walking any distance and we could see that she was in real trouble. Our local vet came and gave her a steroid injection to help build muscle and it did seem to work for a week or so but the second steroid injection didn't have any effect.
 
We noticed at the start of her vomiting and diarrhoea that she had developed a violent reaction to chicken meat, always her favorite. We also found that commercial dog food almost always has chicken meat in it even when labeled Beef, Veal, Turkey or Lamb. Of all the cans whose ingredients we studied we could only find one brand that didn't list chicken among its ingredients.
 
She was by this time off medication. Her vomiting had stopped, the diarrhoea was spasmodic, firm stools one day and diarrhoea the next but her protein levels wouldn't increase whatever we did. She had virtually no muscles left in her legs and it was a struggle for her to stand, but she worked around it.
 
The vet said that she wasn't in pain and we decided that we'd work with Amie and as long as she was bright-eyed, was eating, wagging her tail and going out into the garden for her toilet needs we'd put off making the decision to have her put down as long as there was no pain and she wanted to keep going. Over her last few weeks we'd thought many times that she was close to the end, but she'd always be bright-eyed and happy the next day.
 
Saturday 15th November started off well for her. She ate heartily, was doing lots of tail wagging and we thought she was o.k. During the evening we found her lying in a pool of urine and we knew that this was going to be a bad time for her. She was such a fussy dog that she would never willingly have allowed that to happen. We made her comfortable sat with her, stroked and comforted her and within a couple of hours she gasped a couple of times and it was over for her. We assumed that her biggest muscle, her heart, had shrunk, like the rest of her muscles, and could no longer cope.
 
There's no way that we can prove it, but to us it was so coincidental, the administering of Previcox and her inability to extract protein from her food. She was absolutely fine before the Previcox, all her problems started during the Previcox course.
 
My sister, a people medico in U.K. said that vets don't seem to give animals protective medication (selective COX-2 inhibitor) WITH anti-inflammatories as doctors do to humans.
 
We'll miss her dreadfully, she was part of us as we were part of her. We know that we were lucky to have her for so many years, but we'd hoped that she would grow old gracefully and with dignity, not spending the last 6 months of her life as she did.
 
Fred B.